Cholangiocarcinoma has quietly become one of the clearest proof points that precision oncology can change outcomes—not just theory, but real patients, real time. This talk will show how molecular profiling is reshaping how we diagnose, stratify, and treat this disease. From FGFR2 fusions and IDH1 mutations to emerging targets and mechanisms of resistance, we’ll walk […]

Neddylation is a post-translational modification in which NEDD8 is conjugated to target proteins to regulate their stability, localization, and activity. This process is initiated by NAE1, an E1 enzyme that catalyzes the first step of the transfer. While neddylation dysregulation has been extensively explored in different cancer types and metabolic diseases, its role in brain […]

Professor Carbone (MD, PhD) is an Associate Professor of Hepatology at the University of Milano-Bicocca and Honorary Consultant Hepatologist at the Niguarda Liver Transplant Centre, Milan. He qualified in Medicine in Rome, Italy and trained in hepatology in Italy and in the UK. His research interest mainly relates to study disease mechanisms in autoimmune and […]