Mintegia / Seminario: “The role of programmed cell death in liver disease”

Data / Fecha: 2018ko irailak 20 / 20 de septiembre de 2018
Ordua / Hora: 10:00- 11:00
Lekua / Lugar:  Biodonostia OIIko Prestakuntza Aretoan, 3.Solairua. / IIS Biodonostia, Sala de Formación, Planta 3.
Hizlaria / Ponente: Tom Lüdde (Ph.D) – Department of Gastroenterology, Digestive Diseases and Intensive Care Medicine, University Hospital RWTH Aachen, Germany.

Laburpena / Resumen:
Tom Lüdde (Ph.D) is a distinguished Professor of Gastroenterology, Hepatology and Hepatobiliary Oncology at RWTH Aachen University. In his research, he has been mainly focused on the study of inflammation, cell death and cancer. He has been trying to understand what mechanisms are linking cell death with chronic inflammation, fibrosis and finally cancer development in liver disease. He has laid the groundwork for the identification of the activation of different modes of programmed cell death in chronic liver disease, trying to understand which pathogenic stimuli are activating apoptosis vs. necroptosis in the liver, how these distinct forms of cell death regulate inflammatory responses and regeneration and finally how these processes control fibrosis (activation of hepatic stellate cells) and cancer development.