Last 6-7 October 2022, Prof. Marcos J. Araúzo-Bravo, head of the Computational Biology and Systems Biomedicine Research Group of Biodonostia, hosted in Biodonostia the forth semi-annual meeting of the EU Horizon 2020 funded project (FET-Open) “Circular DNA in diagnosis and disease models” with acronym “Circular Vision”.

Future & Emerging Technologies (FET) are very highly competitive projects that look at innovative ways on developing out-of-this-world technologies coming from various scientific fields.

The aim of our Circular Vision project is to develop and combine novel methods in molecular biology, microfluidics, DNA sequencing and computer biology in order to develop circular DNA as diagnostic markers for Inflammatory Bowel Disease and lung cancer, which then will be adapted to clinical diagnosis and prognosis using advanced image analysis and cytometry methods.

The meeting in Donostia attended by the principal investigators and team members of the partners from 7 EU-research departments from Denmark, Spain, Italy and Switzerland, advisory board members and patient organization guests, discussed the advances of the project in the past six month period and took decisions about the workflow in the coming six months. The meeting had its regular guest lecture, presented by Dr Iker Badiola from UPV, socializing event, and student presentation session.

In Circular Vision, Prof. Arauźo-Bravo from Biodonostia is leading Work Package 1, namely Evolution of circular DNA technologies, and is acting a member of the Steering Committee. As a Work Package leader, he is responsible for coordinating the work and the reporting of the results of work package, and the yearly presentation of the results in front of the European Commission. As a project partner, he is responsible for designing and implementing new tools for mapping and analysis of sequenced circular DNA data, and the analysis and interpretation of data generated by the project.

The first software delivery developed by the Group of Computational Biology of Biodonostia has been selected by the EU innovation radar and has put Biodonostia for the first time on the map of the EU-funded innovations.  (https://www.innoradar.eu/resultbykeyword/biodonostia)