This project explores the potential relationship between endocrine-disrupting chemicals (EDCs) and endometriosis using menstrual blood as a novel, non-invasive biological matrix. The study focuses on compounds such as bisphenol A (BPA) and per- and polyfluoroalkyl substances (PFAS), which have been suggested to interfere with hormonal regulation and may contribute to the development of endometriosis.
A case–control study was conducted in the Basque Country including 45 women of reproductive age, 15 diagnosed with endometriosis and 30 controls. Menstrual blood samples were analyzed to quantify several PFAS and phenols. Contrary to previous findings in the literature, higher levels of several PFAS were observed in controls than in women with endometriosis. In particular, PFOS and PFDeA showed significant inverse associations with the disease.
These results suggest that menstrual blood may reflect different exposure dynamics than traditional biological samples and highlight the need for larger longitudinal studies to better understand the role of environmental contaminants in endometriosis.
Hablaremos de edad cerebral, de reserva cognitiva y presentaré un modelo que trata de relacionar las experiencias vitales, incluido el multilingüismo, con la reserva cerebral y la reserva cognitiva. Presentaré los métodos que usaremos para aproximarnos a una explicación de por qué la gente envejece de formas tan diversas.