Central nervous system-derived extracellular vesicles: the next generation of neural circulating biomarkers in MS disease? Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) which affects millions of people worldwide. The CNS is integrated by glial and neuronal cells, and both release extracellular vesicles (EVs) that

Study of new multi-target directed compounds for the treatment of glioblastoma Glioblastoma is the most prevalent and malignant brain primary tumour. It is characterized by its marked heterogeneity and current therapy includes the maximum surgical removal of the lesion followed by radiation and temozolomide-based chemotherapy and bevacizumab in recurrent cases.

3D neuronal monitoring platforms for electrochemical sensing of neurotransmitters As the world’s population is living longer, neurodegenerative and neurological diseases are becoming a global issue. At the base of several neurological diseases (e.g., Alzheimer’s disease, Parkinson’s disease) there are neurotransmitters dysfunctions. Thus, determination of neurotransmission dynamics is a compelling phenotype

Characterization of cellular behavior within hydrogels Summary: Although metastases are responsible for the majority of deaths associated with cancer, they are the least understood phase of the disease. Thus, there is an urgent need for reliable models for their study. Our goal is to develop an organotypic hydrogel to study

Howy Jacobs katedradunak bisita egingo dio Mitochondrial Health and Longevity taldeari azaroaren 3an, aurrerapen txikiz. 30 bat minutuko hitzaldi bat emango die taldeko kideei mitokondria-termogenesian egin duen lanari buruz. Bertaratzeko interesa duen edozein pertsona ongi etorria izango da eta eskertu genizueke Marina Villarri (marina.villarfernandez@biodonostia.org) edo Ian Holti (ian.holt@biodonostia.org) jakinaraztea antolakuntza

Karine Rizzoti did her phD at the University Paul Sabatier in Toulouse, in France where she studied cell movements during early development, using the amphibian embryo as a model. She then joined the laboratory of Robin Lovell-Badge, at the National Institute for Medical Research in London. Initially interested in mechanisms