Archivo Eventos

Neurological diseases and mental disorders pose a major challenge due to their high prevalence and progressive neuronal degeneration, which often disrupts neurotransmitter release. Among the most critical neurotransmitters are glutamate and dopamine, both deeply involved in key neurophysiological processes and strongly associated with disorders like Parkinson’s, Alzheimer’s, and epilepsy. To

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative diseasecharacterized by the progressive loss of upper and lower motor neurons (MNs),leading to muscle weakness, atrophy, and eventually paralysis andrespiratory failure. A central pathological feature of ALS is TDP-43proteinopathy, which involves both the loss of nuclear function and theaggregation of TDP-43 in the cytoplasm. TDP-43

Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset disease characterized by gradual degeneration of upper and lower motor neurons (MN) which leads to progressive muscle weakness and paralysis. Non-cell autonomous mechanisms are nowadays considered to play a crucial role in its onset and progression. Thus, the skeletal muscle is hypothesized

Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults and is characterized by its high heterogeneity, which makes current treatments have limited efficacy. In this context, both indole-based and multitargeted compounds have emerged as potential strategies for the development of new drugs for the treatment of