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DTSTART;TZID=Europe/Madrid:20260220T133000
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DTSTAMP:20260525T093045
CREATED:20260216T122415Z
LAST-MODIFIED:20260216T122415Z
UID:104319-1771594200-1771597800@bio-gipuzkoa.eus
SUMMARY:MATRIXinCANCER: bridging bioengineered cancer models with the clinic / La propagación de TDP-43 en la ELA y DFT: nuevas perspectivas a partir de modelos de Drosophila melanogaster
DESCRIPTION:Dormancy is a reversible growth-arrest state that allows cancer cells to survive hostile environments and later reactivate under favorable conditions. In breast cancer\, metastatic cells can seed distant organs -often lung and bone- and recurrence may occur decades later. Bioengineered 3D in vitro models enable tuning biophysical and biochemical properties to better recapitulate physiological niches such as the tumor microenvironment (TME). Using hydrogel-based 3D cultures\, our group studies dormancy-supportive and metastatic microenvironments in breast cancer. Incorporating patient-derived cancer cells increases the translational relevance of these models. In MATRIXinCANCER\, in partnership with the Basque Biobank\, we have established workflows across four hospitals to collect breast-cancer–related patient samples to study the TME and develop more complex\, clinically relevant models. By integrating 2D and 3D cultures with TME characterization -through advanced imaging\, immune profiling and other approaches-\, our final goal is to build platforms for personalized drug testing. \n\nTBD
URL:https://bio-gipuzkoa.eus/eu/agenda/matrixincancer-bridging-bioengineered-cancer-models-with-the-clinic-la-propagacion-de-tdp-43-en-la-ela-y-dft-nuevas-perspectivas-a-partir-de-modelos-de-drosophila-melanogaster/
LOCATION:Salón de Actos\, IIS Biogipuzkoa\, Paseo Dr. Begiristain\, s/n\, SAN SEBASTIÁN\, Gipuzkoa\, 20014\, Spain
CATEGORIES:Agenda,Mintegiak,Prestakuntza
ATTACH;FMTTYPE=image/png:https://bio-gipuzkoa.eus/wp-content/uploads/2026/02/2002.png
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